VM has to be down to complete this process. Edit/update VM with the following:
1) Set run on specific host(host with at least two numa nodes)
2) Set Do not migrate VM
3) Choose for example "interleave" mode and NUMA node count equal to some value
(if you choose preferred mode you need to specify this value equal to 1):
NUMA Node Count = 2
Tune Mode = Interleave
4) Open 'Numa Pinning' menu
5) Drag virtual numa node (vNUMA) from right column to some numa node under on the left, and click OK.
6) Now you already must have numa pinning
I hope it will help.